Overview

Innovative ultra low-dose PET/CT quantitative imaging

Now with Q.AC, a new CT reconstruction algorithm developed exclusively for GE PET/CT scanners, ultra-low dose CT attenuation correction (CTAC) techniques are possible while maintaining consistency in PET quantitation.

Benefits

Innovative ultra low-dose PET/CT quantitative imaging

Key benefits of Q.AC

Q.AC offers potential use of significantly lower CT doses in

  • Longitudinal PET treatment assessment 
  • Respiratory gated PET/CT imaging 
  • PET brain imaging
  • Pediatric protocols
  • Clinical research

Q.AC improves quantitative PET accuracy over time in all protocols 

  • Ultra-low dose CTAC 
  • Low dose localization CT 
  • Diagnostic CT with or without contrast

Technology

When imaging at low doses, the CT beam may not be strong enough to fully penetrate through the patient and reach the CT detector in all projections. Inaccurate attenuation measurements generated by incomplete CT data may then lead to variations in PET SUV measurements. The GE exclusive Q.AC technology is designed to maintain accurate HU numbers even at ultra-low dose CT techniques for PET/CT applications. This enables the delivery of consistently accurate and reproducible CTAC and PET/CT fusion.

Case 1

PET Acquisition
Reconstruction: VUE Point FX with SharpIR
Post-injection time: 52 min
Acquisition time: 2.5 min/bed
Injected Dose: 251 MBg (6.8mCi) of 18F-FDG

CT Acquisition
Whole-body low dose CT technique using Q.AC technology.
No diagnostic CT required.

CTDIvol 0.40 mGy
DLP 36.96 mGy-cm
0.3 mSV∙3

Courtesy of Städtisches Klinikum , Karlsruhe, Germany
3. Obtained by EUR-16262 EN, using an adult head factor of 0.0023∙DLP, an adult neck factor of 0.0054, an adult thorax factor of 0,017∙DLP, an abdomen factor of 0.015∙DLP , an adult pelvis factor of 0,019∙DLP and an adult lower limbs factor of 0.009∙DLP

Case 2

PET Acquisition
Reconstruction: VUE Point FX with SharpIR
Post-injection time: 53 min
Acquisitions time: 2.5 min/bed
Injected Dose: 200 MBq (5.4 mCi) of 18F-FDG

CT Acquisitions
Whole-body low dose CT technique using Q.AC technology.
No diagnostic CT required. 

CTDIvol 0.31 mGy
DLP 39 mGy-cm
0.62 mSV∙3

Courtesy of Städtisches Klinikum , Karlsruhe, Germany
3. Obtained by EUR-16262 EN, using an adult head factor of 0.0023∙DLP, an adult neck factor of 0.0054, an adult thorax factor of 0,017∙DLP, an abdomen factor of 0.015∙DLP , an adult pelvis factor of 0,019∙DLP and an adult lower limbs factor of 0.009∙DLP

Case 3

PET Acquisition
Reconstruction: VUE Point FX with SharpIR
Post-injection time: 32 min
Acquisitions time: 20 min
Injected Dose: 197.7 MBq (5.3 mCi) of 18F-FDG

CT Acquisitions
Brain low dose CT technique using Q.AC technology.
No diagnostic CT required.

CTDIvol 0.42 mGy
DLP 8.59 mGy-cm
0.02 mSV∙3

Courtesy of Städtisches Klinikum , Karlsruhe, Germany
3. Obtained by EUR-16262 EN, using an adult head factor of 0.0023∙DLP, an adult neck factor of 0.0054, an adult thorax factor of 0,017∙DLP, an abdomen factor of 0.015∙DLP , an adult pelvis factor of 0,019∙DLP and an adult lower limbs factor of 0.009∙DLP


Related

Disclaimer

1. Q.AC lowers CT attenuation correction dose while maintaining accurate attenuation coefficients designed for improving PET quantitation consistency
2. Obtained by EUR-16262 EN, using an adult head factor of 0.0023∙DLP, an adult neck factor of 0.0054∙DLP, an adult thorax factor of 0,017∙DLP, an abdomen factor of 0.015∙DLP, an adult pelvis factor of 0,019∙DLP and an adult lower limbs factor of 0.009∙DLP

Downloads

Q.Suite Brochure

PDF 407KB
  • Date Created: 5/7/2013
  • Document ID: DOC1036682